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HLA DQ/DR/DP Antibody (Bu26) [FITC]

Novus Biologicals, part of Bio-Techne | Catalog # NB100-64163

Novus Biologicals, part of Bio-Techne
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NB100-64163
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # Bu26

Concentration

0.1 mg/ml

Product Specifications

Immunogen

Made to Human HLA DP DQ DR

Specificity

NB100-64162 recognizes the beta chains of class II human major histocompatibility (MHC) antigens. The antibody reacts with DP, DQ, DR beta chains, which are expressed by antigen presenting cells, B- cells, monocytes and activated T lymphocytes.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for HLA DQ/DR/DP Antibody (Bu26) [FITC]

Application
Recommended Usage

Flow Cytometry

1:10
Application Notes
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS, 1% Bovine Serum Albumin

Preservative

0.09% Sodium Azide

Concentration

0.1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HLA DQ/DR/DP

The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates containing many genes with important immune system roles. In humans, the MHC spans almost 4 megabases of chromosome 6 and includes more than 200 known genes, of which about half have known immmunological functions. The best known genes in the MHC region are the subset that encodes cell-surface antigen-presenting proteins. In humans, these genes are referred to as human leukocyte antigen (HLA) genes. The most intensely studied HLA genes are: HLA A, HLA B, HLA C, HLA DPA, HLA DPB1, HLA DQA1, HLA DQB1, HLA DRA, and HLA DRB1. In humans, the HLA is divided into three regions: Class I, II, and III. The A, B, and C genes belong to HLA class I while the six D genes belong to class II.

Alternate Names

CD, CELIAC1DQ alpha 1 chain, DC-1 alpha chain, DQ-A1, FLJ27088, FLJ27328, GSE, HLA class II histocompatibility antigen, DQ(W3) alpha chain, HLA-DCA, HLA-DQA, leucocyte antigen DQA1, leukocyte antigen alpha chain, major histocompatibility complex, class II, DQ alpha 1, MGC149527, MHC class II antigen, MHC class II DQA1, MHC class II HLA-D alpha glycoprotein, MHC class II HLA-DQ-alpha-1, MHC class II surface glycoprotein, MHC HLA-DQ alpha

Entrez Gene IDs

3117 (Human)

Gene Symbol

HLA-DQA1

UniProt

Additional HLA DQ/DR/DP Products

Product Documents for HLA DQ/DR/DP Antibody (Bu26) [FITC]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HLA DQ/DR/DP Antibody (Bu26) [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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