Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Label

Biotin

Antibody Source

Monoclonal Mouse IgG2B Clone # 466717

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all GRK2 Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human GRK2
Pro468-Leu689
Accession # P25098

Specificity

Detects endogenous human, mouse and rat GRK2 in Western blots.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: GRK2

Adrenergic Receptor beta Kinase 1 (ADRBK1), also known as GRK2, is a member of the G-protein receptor kinase family. A ubiquitous cytosolic enzyme, GRK-2 specifically phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed under high agonist concentrations. Defects in GRK2 coupling with G-protein receptors may lead to heart failure.

Long Name

G protein-coupled Receptor Kinase 2

Alternate Names

ADRBK1, BARK1, Beta-ARK1

Gene Symbol

ADRBK1

Additional GRK2 Products

Product Documents for GRK2 Antibody (466717) [Biotin]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GRK2 Antibody (466717) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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