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GPS2 Antibody (HL2276)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-48675

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-48675

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human, Mouse, Rat, Zebrafish

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # HL2276

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant fragmemt of human GPS2.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit GPS2 Antibody (HL2276) (NBP3-48675) is a recombinant monoclonal antibody validated for use in IHC, WB and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for GPS2 Antibody (HL2276)

GPS2 Antibody (HL2276)

Western Blot: GPS2 Antibody (HL2276) [NBP3-48675] -

Rat tissue extract (50 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with GPS2 antibody [HL2276] (NBP3-48675) diluted at 1:10000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
GPS2 Antibody (HL2276)

Western Blot: GPS2 Antibody (HL2276) [NBP3-48675] -

Various tissue extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with GPS2 antibody [HL2276] (NBP3-48675) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
GPS2 Antibody (HL2276)

Western Blot: GPS2 Antibody (HL2276) [NBP3-48675] -

Whole zebrafish extract (30 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with GPS2 antibody [HL2276] (NBP3-48675) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

Applications for GPS2 Antibody (HL2276)

Application
Recommended Usage

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GPS2

GPS2 encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq]

Alternate Names

AMF-1, G protein pathway suppressor 2, GPS-2, MGC104294, MGC119287, MGC119288, MGC119289

Gene Symbol

GPS2

Additional GPS2 Products

Product Documents for GPS2 Antibody (HL2276)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GPS2 Antibody (HL2276)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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