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GOSR1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-46171

Novus Biologicals, part of Bio-Techne
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NBP3-46171

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Western Blot, ELISA, Serum

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

golgi SNAP receptor complex member 1. (Uniprot# O95249)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Novus Biologicals Rabbit GOSR1 Antibody - BSA Free (NBP3-46171) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for GOSR1 Antibody - BSA Free

GOSR1 Antibody - BSA Free

Western Blot: GOSR1 Antibody - BSA Free [NBP3-46171] -

Western Blot: GOSR1 Antibody - BSA Free [NBP3-46171] - Human liver tissue were subjected to SDS PAGE followed by western blot with (GOSR1 antibody) at dilution of 1:500
GOSR1 Antibody - BSA Free

Immunohistochemistry: GOSR1 Antibody - BSA Free [NBP3-46171] -

Immunohistochemistry: GOSR1 Antibody - BSA Free [NBP3-46171] - Immunohistochemistry of paraffin-embedded human stomach cancer using (GOSR1 antibody) at dilution of 1:50

Applications for GOSR1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:20-1:200

Serum

FC

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: GOSR1/GS28

In eukaryotic cells, the Golgi apparatus receives newly synthesized proteins from the endoplasmic reticulum (ER) and delivers them after covalent modification to their destination in the cell. Although little is known about membrane-tubule-mediated transport, the molecular mechanism for vesicle-mediated transport is quite well understood, occurring through docking of SNAREs on the vesicle with those on the target membrane. (1). Transport of proteins along the exocytotic pathway is primarily achieved by vesicular intermediates. Two proteins, Golgi SNAREs of 27 kDa, GS27, and of 28 kDa, GS28 are important trafficking membrane proteins between the endoplasmic reticulum and the Golgi and between Golgi subcompartments (2). In vitro, GOS-28, A Golgi SNARE of 28 kD, is efficiently packaged into Golgi-derived vesicles, which are most likely COPI coated. Antibodies directed against GOS-28 block its ability to bind alpha-SNAP, partially inhibit transport from the cis to the medial cisternae, and do not inhibit budding of COP-coated vesicles, but do accumulate docked uncoated vesicles (3).

Long Name

Golgi SNAP Receptor Complex Member 1

Alternate Names

GOLIM2, GS28, p28

Gene Symbol

GOSR1

Additional GOSR1/GS28 Products

Product Documents for GOSR1 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GOSR1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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