Flt-3 Ligand/FLT3L Antibody (40406) [DyLight 680]
Novus Biologicals, part of Bio-Techne | Catalog # FAB308Y
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Western Blot, Neutralization
Label
DyLight 680 (Excitation = 692 nm, Emission = 712 nm)
Antibody Source
Monoclonal Mouse IgG1 Clone # 40406
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Flt‑3 Ligand/FLT3L
Thr27-Pro185
Accession # AAA17999
Thr27-Pro185
Accession # AAA17999
Specificity
Detects human Flt-3 Ligand/FLT3L in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse Flt-3 Ligand/FLT3L is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications for Flt-3 Ligand/FLT3L Antibody (40406) [DyLight 680]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Neutralization
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from ascites
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Flt-3 Ligand/FLT3L
Flt-3 Ligand, also known as FLT3L, is a cytokine that promotes the differentiation or expansion of multiple hematopoietic cell lineages including monocytes, immature dendritic cells, and early B cell lineage cells. It synergizes with other cytokines to promote the myeloid differentiation and mobilization of hematopoietic stem cells, to induce NK cell development, and to induce terminal B cell maturation. Flt-3 Ligand/FLT3L is expressed as a dimer by T cells and bone marrow and thymic fibroblasts. Both transmembrane and soluble forms of Flt-3 Ligand/FLT3L signal through the tyrosine kinase receptor Flt-3/Flk-2.
Long Name
fms-like Tyrosine Kinase 3 Ligand
Alternate Names
FLG3L, Flt3L, FLT3LG
Gene Symbol
FLT3LG
Additional Flt-3 Ligand/FLT3L Products
Product Documents for Flt-3 Ligand/FLT3L Antibody (40406) [DyLight 680]
Product Specific Notices for Flt-3 Ligand/FLT3L Antibody (40406) [DyLight 680]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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