Fibulin 1 Antibody (C12) - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-42195
Key Product Details
Species Reactivity
Mouse, Rat
Applications
Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2b Kappa Clone # C12
Format
BSA Free
Concentration
1 mg/ml
Product Specifications
Immunogen
Immunized with recombinant Mouse Fibulin 1 (Uniprot#: Q08879; Cys399-Arg578 (Uniprot#: Q08879)
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2b Kappa
Description
Novus Biologicals Mouse Fibulin 1 Antibody (C12) - BSA Free (NBP3-42195) is a monoclonal antibody validated for use in IHC, WB and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
Scientific Data Images for Fibulin 1 Antibody (C12) - BSA Free
Western Blot: Fibulin 1 Antibody (C12) [NBP3-42195] -
Western Blot: Fibulin 1 Antibody (C12) [NBP3-42195] - Sample: Recombinant Fibulin 1, Mouse.
Immunohistochemistry-Paraffin: Fibulin 1 Antibody (C12) [NBP3-42195] -
Immunohistochemistry-Paraffin: Fibulin 1 Antibody (C12) [NBP3-42195] - DAB staining on IHC-P; Samples: Mouse Uterus Tissue
Immunohistochemistry-Paraffin: Fibulin 1 Antibody (C12) [NBP3-42195] -
Immunohistochemistry-Paraffin: Fibulin 1 Antibody (C12) [NBP3-42195] - DAB staining on IHC-P; Samples: Mouse Uterus Tissue; Primary Ab: 30ug/ml NBP3-42195; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal AntibodyApplications for Fibulin 1 Antibody (C12) - BSA Free
Application
Recommended Usage
Immunocytochemistry/ Immunofluorescence
5-20ug/mL
Immunohistochemistry
5-30ug/mL
Immunohistochemistry-Paraffin
5-30ug/mL
Western Blot
0.01-2ug/mL
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
0.01M PBS, pH7.4, 50% glycerol
Format
BSA Free
Preservative
0.05% Proclin 300
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: Fibulin 1
Fibulin 1 is a matricellular glycoprotein component of the elastic fiber core in connective tissues. It self-aggregates and additionally binds to several extracellular matrix and cellular proteins including Aggrecan, Versican, Fibronectin, ECM1, NOV/CCN3, and pro-HB-EGF. Fibulin 1c enhances ADAMTS-1 mediated cleavage of Aggrecan and Versican and can itself be cleaved by neutrophil elastase or MMP-13. It functions as a bridge between Fibrinogen and Fibrin, enabling Fibrin attachment to the platelet cell surface via Integrin alpha 2 beta 3. Fibulin 1 inhibits cardiomyocyte proliferation and Fibronectin-mediated cell adhesion and can promote bone formation.
Alternate Names
FBLN1, FIBL1
Gene Symbol
FBLN1
Additional Fibulin 1 Products
Product Documents for Fibulin 1 Antibody (C12) - BSA Free
Product Specific Notices for Fibulin 1 Antibody (C12) - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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