FGF acidic/FGF1 Antibody (V8P1G5*F2) - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-50406
![Immunohistochemistry: FGF acidic/FGF1 Antibody (V8P1G5*F2) - BSA Free [NBP2-50406]](https://resources.bio-techne.com/images/products/FGF-acidic-FGF1-Antibody-V8P1G5F2-Immunohistochemistry-NBP2-50406-img0001.jpg "Immunohistochemistry: FGF acidic/FGF1 Antibody (V8P1G5*F2) - BSA Free [NBP2-50406]")
Conjugate
Catalog #
Key Product Details
Species Reactivity
Zebrafish
Applications
Immunohistochemistry, ELISA
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # V8P1G5*F2
Format
BSA Free
Concentration
1 mg/ml
Product Specifications
Immunogen
Ovalbumin-conjugated synthetic peptide LPRQVEQEED (C-terminal sequence)
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Description
The clone number is listed as V8P1G5*F2 in the scientific literature.
Scientific Data Images for FGF acidic/FGF1 Antibody (V8P1G5*F2) - BSA Free
Immunohistochemistry: FGF acidic/FGF1 Antibody (V8P1G5*F2) - BSA Free [NBP2-50406]
Immunohistochemistry: FGF acidic/FGF1 Antibody (V8P1G5F2) [NBP2-50406] - Whole-mount zebrafish embryoApplications for FGF acidic/FGF1 Antibody (V8P1G5*F2) - BSA Free
Application
Recommended Usage
ELISA
1:100 - 1:2000
Immunohistochemistry
1:10 - 1:500
Application Notes
Positive control(s): ELISA - peptide immunogen; IHC - zebrafish embryo.
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
PBS
Format
BSA Free
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: FGF acidic/FGF1
FGF acidic/FGF1, also known as ECGF and HBGF-1, is a secreted mitogen that stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis. FGF1 is released extracellularly as a disulfide-linked homodimer and is stored in complex with extracellular heparan sulfate. The association of FGF1 with heparan sulfate is a prerequisite for its subsequent interaction with FGF receptors. Internalized FGF1 can translocate to the cytosol and to the nucleus. Intracellular FGF1 functions as a survival factor by inhibiting p53 activity and proapoptotic signaling.
Long Name
Fibroblast Growth Factor acidic
Alternate Names
alpha-ECGF, beta-ECGF, FGF acidic, FGF-1, HBGF-1
Gene Symbol
FGF1
Additional FGF acidic/FGF1 Products
Product Documents for FGF acidic/FGF1 Antibody (V8P1G5*F2) - BSA Free
Product Specific Notices for FGF acidic/FGF1 Antibody (V8P1G5*F2) - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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