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FGF acidic/FGF1 Products
FGF acidic/FGF1, also known as ECGF and HBGF-1, is a secreted mitogen that stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis. FGF1 is released extracellularly as a disulfide-linked homodimer and is stored in complex with extracellular heparan sulfate. The association of FGF1 with heparan sulfate is a prerequisite for its subsequent interaction with FGF receptors. Internalized FGF1 can translocate to the cytosol and to the nucleus. Intracellular FGF1 functions as a survival factor by inhibiting p53 activity and proapoptotic signaling.
20 results for "FGF acidic/FGF1" in Products
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FGF acidic/FGF1 Products
FGF acidic/FGF1, also known as ECGF and HBGF-1, is a secreted mitogen that stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis. FGF1 is released extracellularly as a disulfide-linked homodimer and is stored in complex with extracellular heparan sulfate. The association of FGF1 with heparan sulfate is a prerequisite for its subsequent interaction with FGF receptors. Internalized FGF1 can translocate to the cytosol and to the nucleus. Intracellular FGF1 functions as a survival factor by inhibiting p53 activity and proapoptotic signaling.
20 results for "FGF acidic/FGF1" in Products
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Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies
Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies
Contains 4 membranes - each spotted in duplicate with 53 different angiogenesis antibodies
ELISA
| Sensitivity : | 13.9 pg/mL |
| Assay Range : | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
| Applications : | ELISA |
BA
| Source : | E. coli |
| Accession # : | NP_000791 |
| Applications : | Bioactivity |
Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies
Catalog #:
AFL232
BA
| Source : | E. coli |
| Accession # : | NP_000791 |
| Applications : | Bioactivity |
ELISA
| Assay Range : | 125 - 8,000 pg/mL |
| Applications : | ELISA |
WB, Simple Western, IHC, Neut
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Immunohistochemistry, Simple Western, Western Blot |
BA
| Source : | E. coli |
| Accession # : | P05230.1 |
| Applications : | Bioactivity |
Catalog #:
MAB232
WB
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #3117 |
| Applications : | Western Blot |
WB, Neut
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | Block/Neutralize, Western Blot |
WB, Neut
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Block/Neutralize, Western Blot |
Catalog #:
132-FA
BA
| Source : | Bovine Brain |
| Applications : | Bioactivity |
ELISA
| Assay Range : | 12.5 - 800 pg/mL |
| Applications : | ELISA |
WB, IHC
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #939902 |
| Applications : | Immunohistochemistry, Western Blot |
Catalog #:
4686-FA
BA
| Source : | E. coli |
| Accession # : | NP_034327 |
| Applications : | Bioactivity |
Catalog #:
BAF232
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
