Fc gamma RII/RIII (CD32/CD16) Antibody (93) [Alexa Fluor® 488]
Novus Biologicals, part of Bio-Techne | Catalog # NBP1-27946AF488
Key Product Details
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Scientific Data Images for Fc gamma RII/RIII (CD32/CD16) Antibody (93) [Alexa Fluor® 488]
Applications for Fc gamma RII/RIII (CD32/CD16) Antibody (93) [Alexa Fluor® 488]
Block/Neutralize
Flow Cytometry
Immunohistochemistry
Immunohistochemistry-Frozen
Immunoprecipitation
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Background: Fc gamma RII/RIII (CD32/CD16)
Fc gamma RII/CD32 and Fc gamma RIII/CD16 proteins are low/intermediate affinity receptors for polyvalent immune-complexed IgG. Fc gamma RII is expressed on cells of both myeloid and lymphoid lineages as well as on cells of non-hematopoietic origin. Fc gamma RIIA associates with FcR gamma and delivers an activating signal through its cytoplasmic ITAM motif. In contrast, Fc gamma RIIB delivers an inhibitory signal through its ITIM motif. Fc gamma RIIC represents an unequal cross-over event between the IIA and IIB genes. Fc gamma RIII is expressed on NK cells, T cells, monocytes, and macrophages. It is involved in phagocytosis, secretion of enzymes and inflammatory mediators, antibody-dependent cytotoxicity, and clearance of immune complexes.
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Additional Fc gamma RII/RIII (CD32/CD16) Products
Product Documents for Fc gamma RII/RIII (CD32/CD16) Antibody (93) [Alexa Fluor® 488]
Product Specific Notices for Fc gamma RII/RIII (CD32/CD16) Antibody (93) [Alexa Fluor® 488]
Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.