FACA/FANCA Antibody [PerCP]
Novus Biologicals, part of Bio-Techne | Catalog # AF6026C
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
PerCP (Excitation = 490 nm, Emission = 675 nm)
Antibody Source
Polyclonal Goat IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
E. coli-derived recombinant human FACA/FANCA
Tyr35-Arg142
Accession # O15360
Tyr35-Arg142
Accession # O15360
Specificity
Detects human FACA/FANCA in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant mouse FANCA, recombinant human (rh) FANCD2, rhFANCE, rhFANCF, rhFANCG, and rhFANCI is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for FACA/FANCA Antibody [PerCP]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: FACA/FANCA
Defects in FANCA result in Fanconi Anemia, a genetically heterogeneous autosomal recessive disorder characterized by progressive pancytopenia, diverse congenital malformations, and a predisposition to develop malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair. At the cellular level FANCA defects cause a hypersensitivity to DNA-damaging agents, chromosomal instability, and defective DNA repair.
Long Name
Fanconi Anemia, Complementation Group A
Alternate Names
FAA, FAH, FANCA, FANCH
Gene Symbol
FANCA
Additional FACA/FANCA Products
Product Documents for FACA/FANCA Antibody [PerCP]
Product Specific Notices for FACA/FANCA Antibody [PerCP]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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