ErbB3/Her3 Antibody [Biotin] - (Research Grade patritumab Biosimilar)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-28184B

Recombinant Monoclonal Antibody
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NBP3-28184B
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Conjugate
Catalog #
Alexa Fluor 350
NBP3-28184AF350
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Alexa Fluor 405
NBP3-28184AF405
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Alexa Fluor 488
NBP3-28184AF488
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Alexa Fluor 532
NBP3-28184AF532
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Alexa Fluor 594
NBP3-28184AF594
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Alexa Fluor 647
NBP3-28184AF647
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Alexa Fluor 700
NBP3-28184AF700
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Alexa Fluor 750
NBP3-28184AF750
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Alexa Fluor Plus 405
NBP3-28184AFP405
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Alexa Fluor Plus 488
NBP3-28184AFP488
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Alexa Fluor Plus 555
NBP3-28184AFP555
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Alexa Fluor Plus 594
NBP3-28184AFP594
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Alexa Fluor Plus 647
NBP3-28184AFP647
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Alexa Fluor Plus 680
NBP3-28184AFP680
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Allophycocyanin
NBP3-28184APC
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CoraFluor 1
NBP3-28184CL1
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DyLight 350
NBP3-28184UV
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DyLight 405
NBP3-28184V
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DyLight 488
NBP3-28184G
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DyLight 550
NBP3-28184R
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DyLight 594
NBP3-28184DL594
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DyLight 650
NBP3-28184C
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DyLight 680
NBP3-28184FR
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DyLight 755
NBP3-28184IR
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FITC
NBP3-28184F
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HRP
NBP3-28184H
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Janelia Fluor 525
NBP3-28184JF525
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Janelia Fluor 549
NBP3-28184JF549
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Janelia Fluor 646
NBP3-28184JF646
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Janelia Fluor 669
NBP3-28184JF669
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mFluor Violet 450 SE
NBP3-28184MFV450
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mFluor Violet 500 SE
NBP3-28184MFV500
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mFluor Violet 610 SE
NBP3-28184MFV610
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PE
NBP3-28184PE
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PerCP
NBP3-28184PCP
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

Biotin

Antibody Source

Recombinant Monoclonal Human IgG1 expressed in CHO

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ErbB3/Her3 Antibodies »

Product Specifications

Immunogen

ERBB3 / HER3

Reactivity Notes

Predicted species reactivity: Rat

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Description

This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.

For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.

Applications for ErbB3/Her3 Antibody [Biotin] - (Research Grade patritumab Biosimilar)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Recommended applications are based on validated applications from the unconjugated base product NBP3-28184. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: ErbB3/Her3

The ErbB3 gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain. It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation. However it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers including prostate, bladder and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported but they have not been thoroughly characterized.

Long Name

Receptor Tyrosine Protein Kinase ErbB3

Alternate Names

HER3

Gene Symbol

ERBB3

Additional ErbB3/Her3 Products

Product Documents for ErbB3/Her3 Antibody [Biotin] - (Research Grade patritumab Biosimilar)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for ErbB3/Her3 Antibody [Biotin] - (Research Grade patritumab Biosimilar)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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