Endomucin/Mucin -14 Antibody (DMC473) - Chimeric
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-48356
Recombinant Monoclonal Antibody
Key Product Details
Species Reactivity
Human
Applications
Flow Cytometry
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Human IgG1 Clone # DMC473
Concentration
LYOPH mg/ml
Product Specifications
Immunogen
Endomucin/Mucin -14 recombinant protein expressed in mammalian cells (Accession# Q9ULC0). The exact amino acid sequence is proprietary.
Clonality
Monoclonal
Host
Human
Isotype
IgG1
Description
This product is shipped at ambient temperature. Store at -20C to -80C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80C (Avoid repeated freezing and thawing).
Scientific Data Images for Endomucin/Mucin -14 Antibody (DMC473) - Chimeric
Flow Cytometry: Endomucin/Mucin -14 Antibody (DMC473) - Chimeric [NBP3-48356]
Flow cytometry analysis with Anti-Endomucin/Mucin -14 (DMC473) on HEK293 cells transfected with human Endomucin/Mucin -14 (Blue histogram) or HEK293 transfected with irrelevant protein (Red histogram).Applications for Endomucin/Mucin -14 Antibody (DMC473) - Chimeric
Application
Recommended Usage
Flow Cytometry
1:100
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified from cell culture supernatant
Reconstitution
Dissolve the lyophilized antibody in sterile and low endotoxin water. The recommend volume of water is lot specific. Please refer to the instructions printed on the product vial or contact technical support.
Formulation
PBS, pH 7.4, 5-8% Trehalose
Preservative
Trehalose
Concentration
LYOPH mg/ml
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20C in powder form. Store at -80C once reconstituted.
Background: Endomucin
Endomucin (endothelial sialomucin; also Endomucin-1/2 and Mucin-14) is an 80 - 120 kDa glycoprotein member of the Endomucin family of proteins. It is expressed on endothelial cells and depending upon its glycosylation pattern, can serve as either a pro- or anti-adhesive molecule.
Mouse Endomucin precursor is 261 amino acids in length. It is type I transmembrane protein that contains a 170 aa extracellular domain (ECD) (aa 21 - 190) and a 50 aa cytoplasmic region. Three splice variants exist in the ECD of Endomucin. One shows a deletion of aa 91 - 141, a second shows a one aa substitution for aa 91 - 129, and a third shows a one aa substitution for aa 129 - 142. Over aa 21 - 90, mouse Endomucin shares 60% and 30% aa identity with rat and human Endomucin, respectively.
Alternate Names
EMCN, EMCN2, MUC-14
Gene Symbol
EMCN
Additional Endomucin Products
Product Documents for Endomucin/Mucin -14 Antibody (DMC473) - Chimeric
Product Specific Notices for Endomucin/Mucin -14 Antibody (DMC473) - Chimeric
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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