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DPYD Antibody (24GB5990)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-50982

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NBP3-50982-100ul
NBP3-50982-20ul

Key Product Details

Species Reactivity

Human, Rat

Applications

Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Knockdown Validated

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # 24GB5990

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

A synthesized peptide derived from human DPYD (Uniprot: Q12882)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DPYD Antibody (24GB5990)

DPYD Antibody (24GB5990)

Immunocytochemistry/ Immunofluorescence: DPYD Antibody (24GB5990)[NBP3-50982] -

Immunocytochemical staining of H9C2 cells with DPYD antibody (1:1,000). Nuclei were stained blue with DAPI; Dihydropyrimidine dehydrogenase was stained magenta with Alexa Fluor(R) 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 um.
DPYD Antibody (24GB5990)

Flow Cytometry: DPYD Antibody (24GB5990)[NBP3-50982] -

Flow cytometric analysis of DPYDexpression in H9c2 cells using DPYD antibody (1:2,000). Green, isotype control; red, dihydropyrimidine dehydrogenase.
DPYD Antibody (24GB5990)

Western Blot: DPYD Antibody (24GB5990)[NBP3-50982] -

Western blotting analysis using DPYD antibody (1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (1:20,000) respectively. Image was developed using NaQ(TM) ECL Substrate Kit.

Applications for DPYD Antibody (24GB5990)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Knockdown Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: DPYD

DPYD is encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy.

Alternate Names

DHP, DHPDHASE, dihydropyrimidine dehydrogenase, dihydropyrimidine dehydrogenase [NADP+], Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase, DPDMGC132008, EC 1.3.1.2, MGC70799

Gene Symbol

DPYD

Additional DPYD Products

Product Documents for DPYD Antibody (24GB5990)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for DPYD Antibody (24GB5990)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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