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Key Product Details

Species Reactivity

Rat

Applications

Western Blot

Label

PerCP (Excitation = 490 nm, Emission = 675 nm)

Antibody Source

Polyclonal Sheep IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant rat Dkk-1 (R&D Systems, Catalog # 4010-DK)
Ser23-His270
Accession # NP_001099820

Specificity

Detects rat Dkk-1 in direct ELISAs and Western blots. In these formats, approximately 40% cross-reactivity with recombinant mouse Dkk-1 is observed and approximately 20% cross-reactivity with recombinant human Dkk-1 is observed.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for Dkk-1 Antibody [PerCP]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Dkk-1

DKK1 is a secreted factor that has been linked to the function of osteoblasts. Elevated DKK1 levels in bone marrow plasma and peripheral blood from patients with multiple myeloma correlated with the gene-expression patterns of DKK1 and were associated with the presence of focal bone lesions. The production of DKK1, an inhibitor of osteoblast differentiation, by myeloma cells is associated with the presence of lytic bone lesions in patients with multiple myeloma.

Long Name

Dickkopf-1

Alternate Names

Dkk1

Gene Symbol

DKK1

Additional Dkk-1 Products

Product Documents for Dkk-1 Antibody [PerCP]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Dkk-1 Antibody [PerCP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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