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Key Product Details

Species Reactivity

Cotton Rat

Applications

Western Blot, Neutralization

Label

mFluor Violet 610 SE (Excitation = 421 nm, Emission = 613 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # 163426

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

E. coli-derived recombinant cotton rat CXCL10/IP‑10/CRG‑2
Ile22-Val94
Accession # AAL16935

Specificity

Detects cotton rat CXCL10/IP‑10/CRG‑2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human CXCL1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, or 16, recombinant mouse CXCL1, 2, 4, 6, 7, 9, 10, 11, 12, 13, 15 or 16, recombinant rat CXCL1, 2, 3, 5 or recombinant porcine CXCL8  is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for CXCL10/IP-10/CRG-2 Antibody (163426) [mFluor Violet 610 SE]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Neutralization

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CXCL10/IP-10/CRG-2

CXCL10/IP-10 is an ELR- angiostatic chemokine that interacts with CXCR3 to attract Th1 cells, eosinophils, monocytes, and NK cells to sites of inflammation. It is upregulated by activated T lymphocytes, neutrophils, splenocytes, keratinocytes, osteoblasts, astrocytes, endothelial cells, smooth muscle cells, and pancreatic beta cells. CXCL10 contributes to disease pathology in many chronic inflammatory disorders including rheumatoid arthritis, psoriasis, cancer, multiple sclerosis, diabetes, and cardiovascular disease.

Alternate Names

CRG-2, CRG2, IP-10

Gene Symbol

CXCL10

Additional CXCL10/IP-10/CRG-2 Products

Product Documents for CXCL10/IP-10/CRG-2 Antibody (163426) [mFluor Violet 610 SE]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CXCL10/IP-10/CRG-2 Antibody (163426) [mFluor Violet 610 SE]

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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