CXCL1/GRO alpha/KC/CINC-1 Antibody [HRP]
Novus Biologicals, part of Bio-Techne | Catalog # AF275H
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Western Blot, Neutralization
Label
HRP
Antibody Source
Polyclonal Goat IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
E. coli-derived recombinant human CXCL1/GRO alpha/KC/CINC-1 (R&D Systems, Catalog # 275-GR)
Ala35-Asn107
Accession # P09341
Ala35-Asn107
Accession # P09341
Specificity
Detects human CXCL1/GRO alpha/KC/CINC-1 in direct ELISAs. In direct ELISAs, approximately 50% cross-reactivity with recombinant human (rh) GRO beta and rhGRO gamma is observed, less than 25% cross-reactivity with recombinant rat (rr) CINC-1 is observed, less than 15% cross-reactivity with recombinant mouse (rm) KC is observed and no cross-reactivity with rhNAP-2 or rhPF-4 is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for CXCL1/GRO alpha/KC/CINC-1 Antibody [HRP]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Neutralization
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
PBS
Preservative
No Preservative
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: CXCL1/GRO alpha/KC/CINC-1
CXCL1/GRO alpha/KC/CINC-1 is an ELR+ angiogenic chemokine that interacts with CXCR2/IL-8 RB to attract and activate neutrophils. It is produced at sites of microbial infection by macrophages, monocytes, Kupffer cells, hepatocytes, endothelial and epithelial cells, cardiac and vascular smooth muscle cells, fibroblasts, melanocytes, mast cells, and neurons. CXCL1 function is associated with the development and extent of atherosclerosis, Alzheimer’s disease, and tumor angiogenesis.
Alternate Names
CINC-1, CINC1, GRO alpha, KC, MGSA-alpha
Gene Symbol
CXCL1
Additional CXCL1/GRO alpha/KC/CINC-1 Products
Product Documents for CXCL1/GRO alpha/KC/CINC-1 Antibody [HRP]
Product Specific Notices for CXCL1/GRO alpha/KC/CINC-1 Antibody [HRP]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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