CRIM1 Antibody - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP1-80799
Key Product Details
Validated by
Orthogonal Validation
Species Reactivity
Validated:
Human
Cited:
Mouse, Rat
Applications
Validated:
Immunohistochemistry, Immunohistochemistry-Paraffin
Cited:
Immunohistochemistry-Frozen, IF/IHC
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Format
BSA Free
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: LTEYEAGVCEDENWTDDQLLGFKPCNENLIAGCNIINGKCECNTIRTCSNPFEFPSQDMCLSALKRIEEEKPDCSKARCEVQFSPRCPEDSVLIEGYAPPGECCPLP
Reactivity Notes
Immunogen displays the following percentage of sequence identity for non-tested species: Rat (88%). Mouse reactivity reported in scientific literature (PMID: 26545120)
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for CRIM1 Antibody - BSA Free
![Immunohistochemistry-Paraffin: CRIM1 Antibody [NBP1-80799]](https://resources.bio-techne.com/images/products/CRIM1-Antibody-Immunohistochemistry-Paraffin-NBP1-80799-img0005.jpg "Immunohistochemistry-Paraffin: CRIM1 Antibody [NBP1-80799]")
Immunohistochemistry-Paraffin: CRIM1 Antibody [NBP1-80799]
Immunohistochemistry-Paraffin: CRIM1 Antibody [NBP1-80799] - Staining of human liver shows low expression as expected.
Immunohistochemistry-Paraffin: CRIM1 Antibody [NBP1-80799] -
Immunohistochemistry-Paraffin: CRIM1 Antibody [NBP1-80799] -Staining of human placenta shows moderate cytoplasmic positivity in trophoblastic cells.Applications for CRIM1 Antibody - BSA Free
Application
Recommended Usage
Immunohistochemistry
1:50 - 1:200
Immunohistochemistry-Paraffin
1:50 - 1:200
Application Notes
IHC-P HIER pH6 retrieval is recommended.
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
PBS (pH 7.2) and 40% Glycerol
Format
BSA Free
Preservative
0.02% Sodium Azide
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: CRIM1
CRIM1, also known as cysteine rich motor neuron 1, is a type I transmembrane glycoprotein containing an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 CRRs are similar to those in the BMP-binding antagonists such as Chordin. CRIM1 can interact with TGF-beta family ligands to modulate TGF-beta family ligand functions.
Long Name
Cysteine Rich Motor Neuron 1 Protein
Alternate Names
S52
Entrez Gene IDs
51232 (Human)
Gene Symbol
CRIM1
UniProt
Additional CRIM1 Products
Product Documents for CRIM1 Antibody - BSA Free
Product Specific Notices for CRIM1 Antibody - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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