Collagen II Antibody (COL2A1/8810R)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-49076

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-49076-100ug
NBP3-49076-20ug
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Key Product Details

Species Reactivity

Human, Bovine

Applications

Immunohistochemistry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # COL2A1/8810R expressed in CHO

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Collagen II Antibodies »

Product Specifications

Immunogen

bovine collagen type II (CII). (Uniprot: P02458)

Localization

Secreted, Extracellular matrix

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Theoretical MW

190 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Antibody with azide - store at 2 to 8 C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Scientific Data Images for Collagen II Antibody (COL2A1/8810R)

Collagen II Antibody (COL2A1/8810R)

Immunohistochemistry-Paraffin: Collagen II Antibody (COL2A1/8810R) [NBP3-49076] -

Formalin-fixed, paraffin-embedded human kidney stained with Collagen II Antibody (COL2A1/8810R). Inset: PBS instead of primary antibody; secondary only negative control.

Applications for Collagen II Antibody (COL2A1/8810R)

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Collagen II

The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function. In cartilage, Collagen Type II constitutes the bulk of the fibril. Sensitization with Collagen Type II induces an erosive polyarthritis in rats, mice and higher primates which can resemble rheumatoid arthritis and relapsing polychrondritis.

Alternate Names

Chondrocalcin, COL2A1, SEDC

Gene Symbol

COL2A1

Additional Collagen II Products

Product Documents for Collagen II Antibody (COL2A1/8810R)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Collagen II Antibody (COL2A1/8810R)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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