CLOCK Antibody (OTI2H7)
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46311
![Immunohistochemistry: CLOCK Antibody (OTI2H7) [NBP2-46311]](https://resources.bio-techne.com/images/products/CLOCK-Antibody-2H7-Immunohistochemistry-NBP2-46311-img0003.jpg "Immunohistochemistry: CLOCK Antibody (OTI2H7) [NBP2-46311]")
![Immunohistochemistry: CLOCK Antibody (OTI2H7) [NBP2-46311]](https://resources.bio-techne.com/images/products/CLOCK-Antibody-2H7-Immunohistochemistry-NBP2-46311-img0004.jpg "Immunohistochemistry: CLOCK Antibody (OTI2H7) [NBP2-46311]")
Scientific images may be resized, cropped, or adjusted for brightness or contrast for presentation purposes. These updates are limited to presentation and do not affect the underlying scientific interpretation of the data. Where available, additional source data may be provided upon request.
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Validated:
Human, Mouse, Rat
Cited:
Rat
Applications
Validated:
Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot
Cited:
Immunohistochemistry-Paraffin, Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Clone # OTI2H7
Concentration
1 mg/ml
Product Specifications
Immunogen
Human recombinant protein fragment corresponding to amino acids 1-285 of human CLOCK (NP_004889) produced in E.coli.
Reactivity Notes
Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Theoretical MW
95.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Scientific Data Images for CLOCK Antibody (OTI2H7)
In support of our commitment to scientific transparency, some data images have been temporarily removed from this page pending internal review. Contact us for more information.
Immunohistochemistry: CLOCK Antibody (OTI2H7) [NBP2-46311]
Immunohistochemistry: CLOCK Antibody (2H7) [NBP2-46311] - Analysis of Human tonsil tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)![Immunohistochemistry: CLOCK Antibody (OTI2H7) [NBP2-46311]](https://resources.bio-techne.com/images/products/CLOCK-Antibody-2H7-Immunohistochemistry-NBP2-46311-img0001.jpg "Immunohistochemistry: CLOCK Antibody (OTI2H7) [NBP2-46311]")
Immunohistochemistry: CLOCK Antibody (OTI2H7) [NBP2-46311]
Immunohistochemistry: CLOCK Antibody (2H7) [NBP2-46311] - Analysis of Carcinoma of Human pancreas tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)![Immunohistochemistry: CLOCK Antibody (OTI2H7) [NBP2-46311]](https://resources.bio-techne.com/images/products/CLOCK-Antibody-2H7-Immunohistochemistry-NBP2-46311-img0002.jpg "Immunohistochemistry: CLOCK Antibody (OTI2H7) [NBP2-46311]")
Immunohistochemistry: CLOCK Antibody (OTI2H7) [NBP2-46311]
Immunohistochemistry: CLOCK Antibody (2H7) [NBP2-46311] - Analysis of Human bladder tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)Applications for CLOCK Antibody (OTI2H7)
Application
Recommended Usage
Immunohistochemistry
1:150
Immunohistochemistry-Paraffin
1:150
Western Blot
1:2000
Formulation, Preparation, and Storage
Purification
Immunogen affinity purified
Formulation
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20C. Avoid freeze-thaw cycles.
Background: CLOCK
CLOCK levels peak during the late night and the early part of the subjective day. Mutations in CLOCK causes defective transcriptional activity and lengthens the circadian period, leading to abnormal circadian behavior.
CLOCK antibodies are useful tools for research on circadian rythmns, sleep biology and hormonal cycles.
Long Name
Circadian Locomoter Output Cycles Kaput
Alternate Names
BHLHE8, circadian locomoter output cycles protein kaput, Class E basic helix-loop-helix protein 8, clock (mouse) homolog, clock homolog (mouse), EC 2.3.1.48, hCLOCK, KAT13D, KIAA0334bHLHe8circadian locomoter output cycles kaput protein
Gene Symbol
CLOCK
Additional CLOCK Products
Product Documents for CLOCK Antibody (OTI2H7)
Product Specific Notices for CLOCK Antibody (OTI2H7)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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