Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all CLIP170 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human CLIP170. The immunogen is located within amino acids 1340 - 1390 of CLIP170. Amino Acid Squence: CNNYDSDDQEKQSKKKPR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit CLIP170 Antibody - BSA Free (NBP1-76921) is a polyclonal antibody validated for use in WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for CLIP170 Antibody - BSA Free

Western Blot: CLIP170 AntibodyBSA Free [NBP1-76921]

Western Blot: CLIP170 AntibodyBSA Free [NBP1-76921]

Western Blot: CLIP170 Antibody [NBP1-76921] - Rat brain tissue lysate with CLIP170 antibody at (A) 0.5 and (B) 1 ug/ml.
CLIP170 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: CLIP170 Antibody - BSA Free [NBP1-76921] -

Immunocytochemistry/ Immunofluorescence: CLIP170 Antibody - BSA Free [NBP1-76921] - Immunofuorescence of CLIP170 in human brain tissue with CLIP170 antibody at 20 ug/mL.

Applications for CLIP170 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Western Blot

0.5-1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CLIP170

CLIP170 was initially identified as a new type of intermediate filament associated protein that is highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin's disease. Later experiments showed that it is located at microtubule plus ends and is required for the binding of endocytic carrier vesicles. CLIP170 has also been suggested to act with LIS1, a protein implicated in brain development, to regulate dynein/dynactin binding microtubules. Other studies suggest that CLIP170 can influence the formation of lamellipodia and cell invasion by invasive breast cancer cells by regulating the release of kinesin and IQGAP1 from a complex of those proteins, CLIP170 and Rac1. At least two isoforms of CLIP170 are known to exist.

Alternate Names

CAP-GLY domain containing linker protein 1, CLIP, CLIP170, CLIP-170Reed-Sternberg intermediate filament-associated protein, CYLN1MGC131604, cytoplasmic linker 1, Cytoplasmic linker protein 1, Cytoplasmic linker protein 170 alpha-2, Reed-Steinberg cell-expressed intermediate filament-associated protein, Restin, restin (Reed-Steinberg cell-expressed intermediate filament-associated protein), RSNCAP-Gly domain-containing linker protein 1

Gene Symbol

CLIP1

UniProt

NP_002947 (Human)

Additional CLIP170 Products

Product Documents for CLIP170 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CLIP170 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.