Chorionic Gonadotropin beta Chain (hCG beta) Antibody (INN-hCG-24) [CoraFluor™ 1] - (Beta 4 epitope)

Novus Biologicals, part of Bio-Techne | Catalog # NB600-684CL1

Key Product Details

Species Reactivity

Human

Applications

ELISA, Radioimmunodiffusion, Radioimmunoassay

Label

CoraFluor 1

Antibody Source

Monoclonal Mouse IgG1 Clone # INN-hCG-24

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Chorionic Gonadotropin beta Chain (HCG beta) Antibodies »

Product Specifications

Immunogen

Purified human chorionic gonadotropin

Localization

Secreted

Specificity

This is a high affinity antibody recognising the beta 4 epitope on hCG. It is also reactive with hCGbeta, hCGbetacf (fragment), hCGn (nicked), hCGbetan, CTP-hCG, CTP-hCGbeta. It may be used in combination with INN hCG2, 32 and 45. It has minor cross reactivity with hLH and hLHbeta. No cross reaction is observed with hFSH, hTSH, or the glycoprotein hormone alpha chains.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.

For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.

Applications

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Radioimmunoassay

Optimal dilutions of this antibody should be experimentally determined.

Radioimmunodiffusion

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Recommended applications are based on validated applications from the unconjugated base product NB600-684. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: Chorionic Gonadotropin beta Chain (HCG beta)

Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma.

Long Name

Chorionic Gonadotropin beta Chain

Alternate Names

CG-Beta, CGB, CGB3, CGB5, CGB8, Choriogonadotropin Subunit Beta

Gene Symbol

CGB3

Additional Chorionic Gonadotropin beta Chain (HCG beta) Products

Product Documents

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices

Sold for research purposes only under agreement from Massachusetts General Hospital, US Patent No. 12,134,721. A license is required for development of new commercial assay platforms (e.g., microarrays, microfluidics), diagnostic use or other unlicensed uses. Please contact Technical Support for further details: techsupport@bio-techne.com.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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