Chorionic Gonadotropin beta Chain (hCG beta) Antibody (HCGb/459) [Alexa Fluor™ Plus 680]
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-34631AFP680
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin
Label
Alexa Fluor Plus 680
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # HCGb/459
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Recombinant full-length Chorionic Gonadotropin beta Chain (hCG beta) protein (Uniprot: P01233)
Localization
Cytoplasmic, secreted
Specificity
This monoclonal antibody reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG monoclonal antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.
Marker
Pregnancy & Choriocarcinoma Marker
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Applications
Application
Recommended Usage
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Chorionic Gonadotropin beta Chain (HCG beta)
Long Name
Chorionic Gonadotropin beta Chain
Alternate Names
CG-Beta, CGB, CGB3, CGB5, CGB8, Choriogonadotropin Subunit Beta
Gene Symbol
CGB3
Additional Chorionic Gonadotropin beta Chain (HCG beta) Products
- All Products for Chorionic Gonadotropin beta Chain (HCG beta)
- Chorionic Gonadotropin beta Chain (HCG beta) ELISA Kits
- Chorionic Gonadotropin beta Chain (HCG beta) Primary Antibodies
- Chorionic Gonadotropin beta Chain (HCG beta) Proteins and Enzymes
- Chorionic Gonadotropin beta Chain (HCG beta) Simple Plex
Product Specific Notices
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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