CD45RC Antibody (OX-22) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB120-6406

Novus Biologicals, part of Bio-Techne
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NB120-6406-0.025mg
NB120-6406
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Key Product Details

Species Reactivity

Validated:

Rat

Cited:

Rat

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow Cytometry

Cited:

Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OX-22

Format

BSA Free

Concentration

1.0 mg/ml

View all CD45RC Antibodies »

Product Specifications

Immunogen

Phytohaemagglutinin (PHA) -activated rat lymphocytes

Localization

Cell Membrane

Specificity

NB120-6406 recognizes rat CD45RC, the high molecular weight form of the leucocyte common antigen. This antigen is found on B cells, approximately 50% of bone marrow cells, all CD8+ve T cells, but splits CD4+ve T cells into two populations,CD4+ CD45RC (Th 1-like) and CD4+ CD45RC low (Th-2 like). This product is routinely tested in flow cytometry on rat splenocytes.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

Novus Biologicals Mouse CD45RC Antibody (OX-22) - BSA Free (NB120-6406) is a monoclonal antibody validated for use in IHC and Flow. Anti-CD45RC Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for CD45RC Antibody (OX-22) - BSA Free

Flow Cytometry: CD45RC Antibody (OX22) - BSA Free [NB120-6406]

Flow Cytometry: CD45RC Antibody (OX22) - BSA Free [NB120-6406]

Flow Cytometry: CD45RC Antibody (OX22) [NB120-6406] - Analysis using the FITC conjugate of NB120-6406. Staining of rat spleen cells.
Flow Cytometry: CD45RC Antibody (OX22) - BSA Free [NB120-6406]

Flow Cytometry: CD45RC Antibody (OX22) - BSA Free [NB120-6406]

Flow Cytometry: CD45RC Antibody (OX22) [NB120-6406] - Analysis using the Biotin conjugate of NB120-6406. Staining of rat splenocytes.

Applications for CD45RC Antibody (OX-22) - BSA Free

Application
Recommended Usage

Flow Cytometry

1:100

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD45RC

The CD45 family of cell surface glycoprotein antigens exist as a set of isoforms. The patterns of monoclonal antibody recognition of the CD45 phenotypes can be restricted (CD45RA, RB and RC), or broader, such as the CD45 T 200 species. The "restricted" subsets of this group arise as a result of translation of alternatively spliced mRNAs from exons A, B and C (exons 4, 5 and 6), where exons 3-15 encode the extracellular domain of the CD45 molecule. The restricted epitopes are differentially expressed on T and B lymphocytes, including functionally distinct T cells. CD45 (LCA) is a transmembrane phosphotyrosine phosphatase expressed on leucocytes. Myeloid cells do not express the RC isoform.

Alternate Names

B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide

Gene Symbol

PTPRC

UniProt

P04157 (Rat)

Additional CD45RC Products

Product Documents for CD45RC Antibody (OX-22) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CD45RC Antibody (OX-22) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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