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CCR5 Antibody

Catalog # NB100-56337 | Novus Biologicals a Bio-Techne Brand
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NB100-56337
NB100-56337SS

Key Product Details

Species Reactivity

Human

Applications

Simple Western, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

Product Summary for CCR5 Antibody

Immunogen

A synthetic peptide corresponding to amino acids within 300 and 350 of human CCR5 was used as immunogen.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CCR5 Antibody

Western Blot: CCR5 Antibody [NB100-56337] - Analysis of 10 ug of total cell lysate from MCF-7 cells with at 2 ug/ml dilution
Simple Western: CCR5 Antibody [NB100-56337] - Lane view shows a specific band for CCR5 in 0.5 mg/ml of MCF-7 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.

Applications for CCR5 Antibody

Application
Recommended Usage

Simple Western

1:10

Western Blot

1-3 ug/ml
Application Notes
In MCF-7, a 42 kDa band should be observed.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CCR5

Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors (1). The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1 ), eotaxin, as well as several other related chemokines (2-4). Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation (5,6).

Alternate Names

CCR5, CD195

Entrez Gene IDs

1234 (Human)

Gene Symbol

CCR5

Additional CCR5 Products

Product Documents for CCR5 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CCR5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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