Detects canine CD4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human CD4, recombinant mouse CD4, and recombinant feline CD4 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2B

Scientific Data Images for Canine CD4 PE-conjugated Antibody

Detection of CD4 in Lymphocytes in Canine PBMCs by Flow Cytometry.

Lymphocytes in canine peripheral blood mononuclear cells were stained with Mouse Anti-Canine CD4 PE-conjugated Monoclonal Antibody (Catalog # FAB2410P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Canine CD4 PE-conjugated Antibody

Application

Recommended Usage

Flow Cytometry

10 µL/10⁶ cells
Sample: Lymphocytes in canine peripheral blood mononuclear cells

Reviewed Applications

Read 1 review rated 4 using FAB2410P in the following applications:

Flow Cytometry (1 Review)

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: CD4

CD4 is a 56-58 kDa type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. It is expressed on a variety of cell types including T helper cells, follicular helper cells, neurons, T regulatory cells, microglia, and monocytes. CD4 functions in collaboration with the T cell receptor in the recognition of peptide antigens that are presented by class II major histocompatibility complexes. CD4 also has been shown to be a coreceptor of HIV entry and specifically binds gp120, the external envelope glycoprotein of HIV. Over aa 25-401, canine CD4 shares 56% amino acid identity with human CD4.

Alternate Names

CD4

Entrez Gene IDs

920 (Human); 12504 (Mouse); 24932 (Rat); 403931 (Canine); 101864991 (Cynomolgus Monkey); 493775 (Feline)

Gene Symbol

CD4

UniProt

P33705

Additional CD4 Products

Product Documents for Canine CD4 PE-conjugated Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Canine CD4 PE-conjugated Antibody

For research use only

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Canine CD4 PE-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB2410P

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

View all CD4 Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Scientific Data Images for Canine CD4 PE-conjugated Antibody

Detection of CD4 in Lymphocytes in Canine PBMCs by Flow Cytometry.

Applications for Canine CD4 PE-conjugated Antibody

Flow Cytometry

Reviewed Applications

Spectra Viewer

Plan Your Experiments

Formulation, Preparation, and Storage

Purification

Formulation

Shipping

Stability & Storage

Background: CD4

Alternate Names

Entrez Gene IDs

Gene Symbol

UniProt

Additional CD4 Products

Product Documents for Canine CD4 PE-conjugated Antibody

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for Canine CD4 PE-conjugated Antibody

CONTACT INFORMATION

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