CACNA1S Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-47731

Novus Biologicals, part of Bio-Techne
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NBP3-47731
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CACNA1S Antibodies »

Product Specifications

Immunogen

calcium channel, voltage-dependent, L type, alpha 1S subunit. (Uniprot# Q13698)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit CACNA1S Antibody - BSA Free (NBP3-47731) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for CACNA1S Antibody - BSA Free

CACNA1S Antibody - BSA Free

Immunohistochemistry: CACNA1S Antibody - BSA Free [NBP3-47731] -

Immunohistochemistry: CACNA1S Antibody - BSA Free [NBP3-47731] - Immunohistochemistry of paraffin-embedded human skeletal muscle slide using (CACNA1S Antibody) at dilution of 1:50
CACNA1S Antibody - BSA Free

Western Blot: CACNA1S Antibody - BSA Free [NBP3-47731] -

Western Blot: CACNA1S Antibody - BSA Free [NBP3-47731] - Human brain tissue were subjected to SDS PAGE followed by western blot with (CACNA1S antibody) at dilution of 1:1000

Applications for CACNA1S Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:20-1:200

Western Blot

1:500-1:2000
Application Notes
Theoretical Molecular Weight is 200-220 kDa

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CACNA1S

Voltage-sensitive calcium channels mediate the entry of calcium into many types of excitable cells and thus play a key role in neurotransmitter release and excitation-contraction (E-C) coupling. The 1,4-dihydropyridines (DHPs) are synthetic organic compounds which can be used to identify the L-type calcium channels that are found in all types of vertebrate muscle, neuronal and neuroendocrine cells. The DHP receptor is part of the L-type calcium channel complex and is thought to be the voltage sensor in E-C coupling.The purified DHP receptor isolated from triads is composed of at least four subunits. The alpha-1 subunit contains the binding site for the DHPs and shows high sequence homology to the voltage gated sodium channel. The alpha-2 subunit is a large glycoprotein associated with the DHP receptor which was first described in skeletal muscle and is also found in high concentrations in other excitable tissues such as cardiac muscle and brain and in low concentrations in most other tissues studied. The other two subunits that co-purify with the DHP receptor are termed beta and gamma.

Long Name

Voltage-dependent L-type calcium channel subunit alpha-1S

Alternate Names

CACH1, CACN1, CACNL1A3, Cav1.1, MHS5

Gene Symbol

CACNA1S

Additional CACNA1S Products

Product Documents for CACNA1S Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CACNA1S Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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