C5L2/GPR77 Antibody (DMC482) - Chimeric

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-48366

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-48366-100ug
NBP3-48366-10ug
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # DMC482

Concentration

LYOPH mg/ml

View all C5L2/GPR77 Antibodies »

Product Specifications

Immunogen

C5L2/GPR77 recombinant protein expressed in mammalian cells (Accession# Q9P296). The exact amino acid sequence is proprietary.

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Description

This product is shipped at ambient temperature. Store at -20C to -80C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80C (Avoid repeated freezing and thawing).

Scientific Data Images for C5L2/GPR77 Antibody (DMC482) - Chimeric

C5L2/GPR77 Antibody (DMC482) - Chimeric

Flow Cytometry: C5L2/GPR77 Antibody (DMC482) - Chimeric [NBP3-48366]

Flow cytometry analysis with Anti-C5L2/C5L2/GPR77 (DMC482) on HEK293 cells transfected with human C5L2/C5L2/GPR77 (Blue histogram) or HEK293 transfected with irrelevant protein (Red histogram).

Applications for C5L2/GPR77 Antibody (DMC482) - Chimeric

Application
Recommended Usage

Flow Cytometry

1:100

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified from cell culture supernatant

Reconstitution

Dissolve the lyophilized antibody in sterile and low endotoxin water. The recommend volume of water is lot specific. Please refer to the instructions printed on the product vial or contact technical support.

Formulation

PBS, pH 7.4, 5-8% Trehalose

Preservative

Trehalose

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C in powder form. Store at -80C once reconstituted.

Background: C5L2/GPR77

Official Gene Symbol: GPR77 Gen Bank Accession Number: NP_060955 Gene ID: 27202 (human) Gene Map Locus: 19q13.33 (human) C5L2 is 337A.A orphan member that belongs to anaphylatoxin receptor family. It is a seven transmembrane G-protein-coupled receptor consisting of an N-terminal N-glycosylation site, several conserved cysteines and several potential C-terminal phosphorylation sites. It binds to C5a and C5a-des-Arg and serves as a highly regulated scavenger receptor with a negative modulatory influence on C5aR-mediated inflammation. Northern Blot analysis suggests it is co- expressed along with C5aR in different tissues and cells including neutrophils/macrophages, mast cells, dendritic cells, brain, lung, heart, kidney, liver, ovary and testis.

Long Name

C5a Anaphylatoxin Chemotactic Receptor C5L2

Alternate Names

GPR77

Gene Symbol

C5AR2

Additional C5L2/GPR77 Products

Product Documents for C5L2/GPR77 Antibody (DMC482) - Chimeric

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for C5L2/GPR77 Antibody (DMC482) - Chimeric

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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