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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Polyclonal Goat IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

E. coli-derived recombinant human BMP-3
Ser346-Arg472
Accession # P12645

Specificity

Detects human BMP-3 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) BMP-2, rhBMP-4, rhBMP-5, rhBMP-6, and rhBMP-7 is observed. This antibody very weakly recognizes native dimeric BMP-3.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for BMP-3 Antibody [PE]

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: BMP-3

Bone morphogenetic protein 3 (BMP3) is a 472 amino acid member of the bone morphogenetic protein (BMP) family. BMP3 negatively regulates bone density and is a member of the TGF beta superfamily. It is highly expressed in fracture tissue, predominantly in osteoblasts, osteoclasts and chondroblasts. It may play a role in otosclerosis, osteosarcoma, osteogenesis imperfecta, osteomalacia and periodontitis.

Long Name

Bone Morphogenetic Protein 3

Alternate Names

BMP3, Osteogenin

Gene Symbol

BMP3

Additional BMP-3 Products

Product Documents for BMP-3 Antibody [PE]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for BMP-3 Antibody [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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