BMP-15/GDF-9B Antibody - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-81743
![Immunohistochemistry: BMP-15/GDF-9B Antibody - BSA Free [NBP2-81743]](https://resources.bio-techne.com/images/products/BMP-15-GDF-9B-Antibody-Immunohistochemistry-NBP2-81743-img0001.jpg "Immunohistochemistry: BMP-15/GDF-9B Antibody - BSA Free [NBP2-81743]")
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Format
BSA Free
Concentration
1 mg/ml
Product Specifications
Immunogen
Rabbit polyclonal BMP15 antibody was raised against an 18 amino acid peptide near the amino terminus of human BMP15. The immunogen is located within amino acids 60 - 110 of BMP15. Amino Acid Squence: LYRRSADSHGHPRENRTI
Reactivity Notes
Immunogen displays the following percentage of sequence identity for non-tested species: Mouse: (89%), Sheep: (83%), Bovine: (83%)
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Theoretical MW
43 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Description
Novus Biologicals Rabbit BMP-15/GDF-9B Antibody - BSA Free (NBP2-81743) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
Scientific Data Images for BMP-15/GDF-9B Antibody - BSA Free
Immunohistochemistry: BMP-15/GDF-9B Antibody - BSA Free [NBP2-81743]
Immunohistochemistry: BMP-15/GDF-9B Antibody [NBP2-81743] - Analysis of BMP-15/GDF-9B in human prostate tissue with BMP-15/GDF-9B antibody at 10 ug/ml.Applications for BMP-15/GDF-9B Antibody - BSA Free
Application
Recommended Usage
Western Blot
1-2 ug/ml
Formulation, Preparation, and Storage
Purification
Peptide affinity purified
Formulation
PBS
Format
BSA Free
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: BMP-15/GDF-9B
BMP-15 (Bone morphogenetic protein 15), also known as GDF-9B, is a TGF-b superfamily ligand that is expressed by oocytes throughout folliculogenesis and plays an important role in oocyte development. BMP-15 promotes the FSH-independent proliferation of ovarian granulosa cells (GC) and induces GC glycolysis and cholesterol synthesis. BMP-15 blocks the FSH-induced GC expression of FSH R and multiple steroidogenic molecules. BMP-15 exerts is effects through interactions with BMPR-IB/ALK6 and BMPR-II, and nonphosphorylated BMP-15 functions as a competitive antagonist at BMPR-IB. Mature BMP-15 forms 34 kDa noncovalently-linked homodimers and 37 kDa heterodimers with mature GDF-9.
Long Name
Bone Morphogenetic Protein 15
Alternate Names
BMP15, GDF-9B
Gene Symbol
BMP15
Additional BMP-15/GDF-9B Products
Product Documents for BMP-15/GDF-9B Antibody - BSA Free
Product Specific Notices for BMP-15/GDF-9B Antibody - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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