Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry

Label

Janelia Fluor 525

Antibody Source

Polyclonal Goat IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all beta-Arrestin 1 Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human beta-Arrestin 1
Met1-Arg418
Accession # P49407

Specificity

Detects human beta-Arrestin 1 in direct ELISAs. In direct ELISAs, less than 1% cross-reactivity with recombinant human beta-Arrestin 2 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for beta-Arrestin 1 Antibody [Janelia Fluor® 525]

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: beta-Arrestin 1

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization ofG-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones,neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in thebeta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the centralnervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin systemis believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcriptsencoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known.(provided by RefSeq)

Alternate Names

ARR1, ARRB1, betaArrestin 1

Gene Symbol

ARRB1

Additional beta-Arrestin 1 Products

Product Documents for beta-Arrestin 1 Antibody [Janelia Fluor® 525]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for beta-Arrestin 1 Antibody [Janelia Fluor® 525]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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