BCAP31 Antibody (23GB3680)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-51126

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NBP3-51126-100ul
NBP3-51126-20ul
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Knockdown Validated

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # 23GB3680

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all BAP31 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human BCAP31 (Uniprot: P51572)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for BCAP31 Antibody (23GB3680)

BCAP31 Antibody (23GB3680)

Immunocytochemistry/ Immunofluorescence: BCAP31 Antibody (23GB3680)[NBP3-51126] -

Immunocytochemical staining of HepG2 cells with BCAP31 antibody (1:1,000). Nuclei were stained blue with DAPI; BCAP31 was stained magenta with Alexa Fluor(R) 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 um.
BCAP31 Antibody (23GB3680)

Flow Cytometry: BCAP31 Antibody (23GB3680)[NBP3-51126] -

Flow cytometric analysis of BCAP31expression in HepG2 cells using BCAP31 antibody (1:2,000). Green, isotype control; red, B cell receptor associated protein 31.
BCAP31 Antibody (23GB3680)

Western Blot: BCAP31 Antibody (23GB3680)[NBP3-51126] -

Western blotting analysis using BCAP31 antibody (1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (1:20,000) respectively. Image was developed using FeQ(TM) ECL Substrate Kit.

Applications for BCAP31 Antibody (23GB3680)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Knockdown Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: BAP31

BAP31 (B Cell Receptor Associated Protein, 28 kDa) is a multiple membrane spanning protein of the endoplasmic reticulum. It has been shown to form both homo and hetero oligomers with the closely related BAP29, and is a potential apoptotic regulator as a predicted BCL2/BCLXL associated protein. In the C terminal domain of BAP31, there are two identical recognition sites for initiator Caspases 1 and 8 of the programmed death cascade. It is hypothesized that BAP31 plays a role in the transport of selected proteins to the Golgi apparatus. BAP31 has also been shown to control expression of CFTR (cystic fibrosis transmembrane conductance regulator). It is believed that interference with the expression or function of BAP31 in epithelial cells may be a way to circumvent the chloride channel defect in cystic fibrosis.

Long Name

B-cell Receptor-associated Protein 31

Alternate Names

6C6-Ag, BCAP31

Gene Symbol

BCAP31

Additional BAP31 Products

Product Documents for BCAP31 Antibody (23GB3680)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for BCAP31 Antibody (23GB3680)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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