Androgen Receptor V7 Antibody (DHTR.V7/9125R) [Alexa Fluor® 488]
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24285AF488
Recombinant Monoclonal Antibody
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry-Paraffin
Label
Alexa Fluor 488 (Excitation = 488 nm, Emission = 515-545 nm)
Antibody Source
Recombinant Monoclonal Rabbit IgG Kappa Clone # DHTR.V7/9125R
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Recombinant fragment (around aa600-920) of human Androgen Receptor protein (Androgen Receptor-V7 specific) (exact sequence is proprietary)
Localization
Nucleus.
Specificity
AR V7 belongs to the nuclear hormone receptor family. It contains the nuclear receptor DNA binding domain. Steroid hormone receptors are ligand-activated transcription factors that regulate the expression of eukaryotic genes affecting cell proliferation and differentiation in target tissues. The activity of transcription factors is regulated by binding co-activators and co-repressors. This target is a splice variant of the androgen receptor that lacks the C-terminal androgen-binding site. AR-V7 plays an important role in the occurrence, development and drug resistance of prostate cancer.
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG Kappa
Applications for Androgen Receptor V7 Antibody (DHTR.V7/9125R) [Alexa Fluor® 488]
Application
Recommended Usage
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Androgen Receptor V7
Alternate Names
AIS, androgen receptor, AR8, DHTR, dihydrotestosterone receptor, HUMARA, HYSP1, KD, NR3C4, Nuclear receptor subfamily 3 group C member 4, SBMA, SMAX1, TFM
Gene Symbol
AR
Additional Androgen Receptor V7 Products
Product Documents for Androgen Receptor V7 Antibody (DHTR.V7/9125R) [Alexa Fluor® 488]
Product Specific Notices for Androgen Receptor V7 Antibody (DHTR.V7/9125R) [Alexa Fluor® 488]
Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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