Activin C/Inhibin beta C Antibody (CL6915) [DyLight 350]
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-44442UV
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Label
DyLight 350 (Excitation = 353 nm, Emission = 432 nm)
Antibody Source
Monoclonal Mouse IgG1 Clone # CL6915
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
This antibody was generated using a recombinant protein sequence of P55103, with the exact immunogen sequence remaining proprietary.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Activin C
Activins and Inhibins are TGF beta superfamily proteins that regulate a wide range of processes including mesoderm induction, reproductive system development and function, liver growth and regeneration, wound healing, and inflammation. Activins signal through heterodimeric receptor complexes composed of type I (Activin RIA or RIB) and type II (Activin RIIA or RIIB) transmembrane Ser/Thr kinases. Activin C is expressed as an approximately dimer predominantly by hepatocytes but also by multiple cell types in the male and female reproductive tracts, posterior pituitary and adrenal glands, and nociceptive afferent dorsal root ganglia neurons. It regulates Activin induced effects in a variety of systems by forming intracellular dimers with the Activin A subunit and impeding the release of Activins A and AB. It functions extracellularly by interfering with Activin A‑receptor interactions. Activin C can additionally form heterodimers with the Activin B or E subunits.
Alternate Names
INHBC
Gene Symbol
INHBC
Additional Activin C Products
Product Documents for Activin C/Inhibin beta C Antibody (CL6915) [DyLight 350]
Product Specific Notices for Activin C/Inhibin beta C Antibody (CL6915) [DyLight 350]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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