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ACK1 Antibody, Novus Biologicals

Bio-Techne includes Novus Biologicals | Catalog # H00010188-D01P

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H00010188-D01P

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for ACK1 Antibody

Immunogen

TNK2 (AAH08884.1, 1 a.a. - 352 a.a.) full-length human protein. MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKALCKRKSWMSKVFSGKRLEAEFPPHHSQSTFRKTSPAPGGPAGEGPLQSLTCLIGEKDLRLLEKLGDGSFVVVRRGEWDAPSGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKPPWRDISASSSTQFPHAVPCFPTSLLAKLLLRHSVPASSREIKLVSILC

Specificity

Reacts with tyrosine kinase, non-receptor, 2.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ACK1 Antibody

Western Blot: ACK1 Antibody [H00010188-D01P] - Analysis of TNK2 expression in IMR-32.
Immunocytochemistry/Immunofluorescence: ACK1 Antibody [H00010188-D01P] - Analysis of antibody to TNK2 on HeLa cell. Antibody concentration 20 ug/ml.
Western Blot: ACK1 Antibody [H00010188-D01P] - Analysis of TNK2 expression in transfected 293T cell line by TNK2 polyclonal antibody.Lane 1: TNK2 transfected lysate(39.80 KDa).Lane 2: Non-transfected lysate.

Applications for ACK1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is reactive against transfected lysate in western blot, and as a detection antibody in ELISA.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ACK1

This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq]

Long Name

Activated CDC42 kinase 1

Alternate Names

TNK2

Entrez Gene IDs

10188 (Human)

Gene Symbol

TNK2

Additional ACK1 Products

Product Documents for ACK1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ACK1 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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