Catestatin

Tocris Bioscience, part of Bio-Techne | Catalog # 2722

Non-competitive nAChR antagonist
Discontinued Product
2722 has been discontinued. View all Additional Nicotinic Receptor Antagonists products.

Key Product Details

Description

Non-competitive nAChR antagonist

Alternative Names

Chromogranin A344-364

View all Additional Nicotinic Receptor Antagonists »

Product Description

Catestatin is a non-competitive nicotinic cholinergic antagonist; selectively inhibits nicotinic-stimulated catecholamine secretion from chromaffin cells and noradrenergic neurons (IC50 ~ 200 nM). Blocks nicotinic-induced cationic signaling (IC50 ~ 200 - 250 nM) and inhibits nicotinic-agonist induced desensitization of catecholamine release. Also stimulates mast cell release of histamine via a separate mechanism.

Product Specifications

Molecular Weight

2425.84

Formula

C107H173N37O26S

Storage

Store at -20°C

CAS Number

142211-96-9

PubChem ID

16143960

InChI Key

HCEYIDADOJWYIM-DIWOTYQXSA-N

SMILES

[H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in water

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Catestatin

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Catestatin

For research use only

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