3'-Phosphoadenosine-5'-phosphosulfate Best Seller
R&D Systems, part of Bio-Techne | Catalog # ES019
Substrate for sulfotransferase assay
Key Product Details
Species
Multi-Species
Formulation, Preparation, and Storage
Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -70 °C for up to six months. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: PAPS
3'-Phosphoadenosine-5'-phosphosulfate (PAPS) is the universal sulfur donor for sulfotransferases. It is synthesized from ATP through two steps. In the first step, one ATP molecule is converted to adenosine-5'-phosphosulfate (APS) by ATP sulfurylase and pyrophosphate (PPi) is generated as a byproduct. In the second step, the APS is converted to PAPS by APS kinase and ADP is generated as a byproduct. To drive the reaction forward, the pyrophosphate can be further degraded to phosphate (Pi) by inorganic pyrophosphatase to eliminate feedback inhibition, and the ADP can be converted back to ATP using pyruvate kinase.
Long Name
3'-Phosphoadenosine-5'-Phosphosulfate
Additional PAPS Products
Product Documents for 3'-Phosphoadenosine-5'-phosphosulfate
Product Specific Notices for 3'-Phosphoadenosine-5'-phosphosulfate
For research use only
Loading...
Loading...
Loading...