ZAP70: Small Molecules and Peptides
ZAP70 is a cytoplasmic tyrosine kinase that is essential for TCR signal transduction. It is expressed in T and NK cells, associates with the TCR zeta chain, and is phosphorylated upon TCR stimulation. This activates ZAP70, which subsequently interacts with several Sh2 or PTB-containing adaptors and enzymes such as Vav, Shc Abl and Lck.
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1 result for "ZAP70 Small Molecules and Peptides" in Products
ZAP70: Small Molecules and Peptides
ZAP70 is a cytoplasmic tyrosine kinase that is essential for TCR signal transduction. It is expressed in T and NK cells, associates with the TCR zeta chain, and is phosphorylated upon TCR stimulation. This activates ZAP70, which subsequently interacts with several Sh2 or PTB-containing adaptors and enzymes such as Vav, Shc Abl and Lck.
Zap70 inhibitor; inhibits interaction with ITAMs
| Chemical Name: | 5-Chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-4-pyrimidinecarboxamide |
| Purity: | ≥98% (HPLC) |
