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66 results for "UNC5H3" in Products

UNC5H3 Products

Members of the UNC5H family are best known as receptors for the axon guidance molecule netrin. Structurally, UNC5Hs have two Ig and two thrombospondin type 1 domains in their extracellular region, and a conserved ZU-5 domain, a deleted in colorectal cancer (DCC)-binding domain, and a C-terminal death domain in their cytoplasmic region. In general, they mediate the chemorepulsive effects of netrin, while the other netrin receptor subtype, DCC, mediates attraction. Members of the UNC5H family have also been implicated as tumor suppressors and regulators of apoptosis.

Source: NS0
Accession #: O95185
Applications: Bind
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Human, Mouse
Details: Goat IgG Polyclonal
Applications: IHC, ELISA, ICC/IF
Immunocytochemistry/ Immunofluorescence: UNC5H3/UNC5C Antibody [NBP1-37002]
(2)
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: WB
Western Blot: UNC5H3/UNC5C Antibody [NBP1-69283]
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