Ubiquitin E1 Enzyme/UBE1L2 Products

Ubiquitin-activating Enzyme 1-like 2 (UBE1L2), also known as Ubiquitin-like Modifier Activating Enzyme 6 (UBA6), is a 1052 amino acid (aa) member of the Ubiquitin-activating (E1) enzyme family with a predicted molecular weight of 118 kDa. The mouse and rat UBE1L2/UBA6 orthologs share 88% aa sequence identity with the human protein. UBE1L2/UBA6 is expressed in vertebrate cells where four isoforms have been identified. UBE1L2/UBA6 is an activating enzyme for both Ubiquitin and FAT10 via a similar ...