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159 results for "TRF-2" in Products

TRF-2 Products

RF2 (telomeric repeat-binding factor 2; also telomeric DNA-binding protein) is a 55-60 kDa, ubiquitously expressed nuclear protein that participates in telomere homeostasis. TRF2 binds as a dimer to TTAGGG repeats at ends of chromosomes (telomeres), where it blocks inappropriate activation of the ATM/p53 pathway. It also collaborates with TRF1 to promote normal telomere length. TRF2 has been found up regulated in several human cancers. Human TRF2 is 500 amino acids (aa) in length. It ...

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Catalog #: AF5635AFP555
Catalog #: AF5635AFP647
Catalog #: FAB5635AFP594
Catalog #: AF5635AFP488
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