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11 results for "TIMP-1" in Products

TIMP-1 Products

TIMP-1 (tissue inhibitor of metalloproteinase-1) is a secreted glycoprotein that blocks metalloproteinase (MMP) activity. It circulates in complex with various MMPs to maintain them in an inactive state. It is produced by fibroblasts, osteoblasts, endothelial cells, granulosa cells, dendritic cells, vascular smooth muscle cells, adipocytes, and monocytes. TIMP-1 also protects against apoptosis in B cells, stimulates erythropoiesis and BFU-E expansion, both stimulates and inhibits tumor growth, inhibits angiogenesis, and stimulates gonadal steroidogenesis in conjuction with Cathepsin L.

Reactivity:
Human
Assay Range:
0.156-10 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva)
Applications:
ELISA
Human TIMP-1 ELISA Standard Curve
(2)
Reactivity:
Mouse
Assay Range:
37.5-2400 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma)
Applications:
ELISA
Mouse TIMP-1 ELISA Standard Curve
(2)
Reactivity:
Rat
Assay Range:
37.5-2400 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma)
Applications:
ELISA
Rat TIMP-1 ELISA Standard Curve
(2)
Reactivity:
Human
Assay Range:
4.68-300 pg/ml (example only; lot dependent)
Applications:
ELISA

Recombinant Monoclonal Antibody

Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #TIMP1/1944R
Applications:
ELISA
Novus Antibodies
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