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2 results for "TGF-beta 1" in Products
TGF-beta 1 Products
TGF-beta 1 (Transforming Growth Factor beta 1) is a pleiotrophic cytokine that regulates immune function, proliferation, and epithelial-mesenchymal transition. TGF-beta 1 associates with LAP to form a latent complex. It can be is activated from latency by plasmin, matrix metalloproteases, thrombospondin 1, and a subset of integrins. TGF-beta 1 signals through complexes of TGF-beta RII with TGF-beta RI/ALK-5 or ALK-1. TGF-beta signaling is modulated by the accessory receptors TGF-beta RIII/Betaglycan and Endoglin/CD105.
Reactivity:
Rat
Assay Range:
2.74-2000 pg/mL (example only; lot dependent)
Reactivity:
Porcine
Assay Range:
13.7-10000 pg/mL (example only; lot dependent)