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SMURF2 Products
SMURF-2 (SMAD ubiquitin regulatory factor-2) is an approximately 86 kDa, 748 amino acid cytoplasmic E3 ubiquitin ligase that negatively regulates TGF-beta signaling by promoting proteasomal degradation of some SMAD signaling molecules. It also influences cell cycle progression, peaking during mitosis and binding MAD2L1 and NEDD9/CASL.
2 results for "SMURF2" in Products
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SMURF2 Products
SMURF-2 (SMAD ubiquitin regulatory factor-2) is an approximately 86 kDa, 748 amino acid cytoplasmic E3 ubiquitin ligase that negatively regulates TGF-beta signaling by promoting proteasomal degradation of some SMAD signaling molecules. It also influences cell cycle progression, peaking during mitosis and binding MAD2L1 and NEDD9/CASL.
2 results for "SMURF2" in Products
HECT E3 ubiquitin ligase inhibitor
| Chemical Name : | N-(4-Acetylphenyl)-3-(5-ethyl-2-furanyl)-2-propenamide |
| Purity : | ≥98% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #690638 |
| Applications : | Western Blot |
