SLC7A7 is the light subunit of a cationic amino acid transporter that dimerizes with the heavy subunit transporter protein SLC3A2 (CD98). It is expressed on epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in SLC7A7 are a cause of lysinuric protein intolerance.
SLC7A7 is the light subunit of a cationic amino acid transporter that dimerizes with the heavy subunit transporter protein SLC3A2 (CD98). It is expressed on epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in SLC7A7 are a cause of lysinuric protein intolerance.
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