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Siglec-8 Products
Siglec-8, also known as SAF, is a transmembrane lectin that is expressed on eosinophils, basophils, and mast cells and shows a binding preference for the carbohydrate 6-O sulfated sLe(x). The functional paralog of human Siglec-8 is known as Siglec-F in mouse. Cross-linking of Siglec-8 inhibits Fc epsilon RI alpha induced mast cell degranulation. It also induces eosinophil apoptosis, an effect which is enhanced by the eosinophil-activating cytokines IL-5, IL-33, and GM-CSF.
13 results for "Siglec-8" in Products
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Siglec-8 Products
Siglec-8, also known as SAF, is a transmembrane lectin that is expressed on eosinophils, basophils, and mast cells and shows a binding preference for the carbohydrate 6-O sulfated sLe(x). The functional paralog of human Siglec-8 is known as Siglec-F in mouse. Cross-linking of Siglec-8 inhibits Fc epsilon RI alpha induced mast cell degranulation. It also induces eosinophil apoptosis, an effect which is enhanced by the eosinophil-activating cytokines IL-5, IL-33, and GM-CSF.
13 results for "Siglec-8" in Products
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #837535 |
| Applications : | CyTOF-ready, Flow Cytometry |
| Source : | NS0 |
| Accession # : | AAH53319 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #837535 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #837535 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #837535 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #837535 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #837535 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #837535 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #837535 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #837535 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #837535 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #837535 |
| Applications : | Flow Cytometry |
