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RIPK3/RIP3 Products

RIPK3 (), also known as RIP3, is a 518 amino acid (aa), 60 kDa phosphoprotein that contains an N-terminal protein kinase domain and a C-terminal interaction motif with which it binds RIPK1. It converts cell response to TNF-alpha from apoptosis (RIPK1 via Fas) to programmed necrosis (RIPK1/RIPK3) by inducing reactive oxygen species production. Alternately spliced human beta (252 aa) and gamma (231 aa) isoforms diverge after aa 219 and 221, respectively, and are found to antagonize RIP3.

6 results for "RIPK3/RIP3" in Products

RIPK3/RIP3 Products

RIPK3 (), also known as RIP3, is a 518 amino acid (aa), 60 kDa phosphoprotein that contains an N-terminal protein kinase domain and a C-terminal interaction motif with which it binds RIPK1. It converts cell response to TNF-alpha from apoptosis (RIPK1 via Fas) to programmed necrosis (RIPK1/RIPK3) by inducing reactive oxygen species production. Alternately spliced human beta (252 aa) and gamma (231 aa) isoforms diverge after aa 219 and 221, respectively, and are found to antagonize RIP3.

6 results for "RIPK3/RIP3" in Products

WB, ICC

Recombinant Monoclonal Antibody.

Catalog #: RDC2118
WB

Recombinant Monoclonal Antibody.

Necroptosis inhibitor; also inhibits pyroptosis

Potent and selective RIP3 kinase inhibitor

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