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4 results for "PROTACs (Proteolysis Targeting Chimeras)" in Products
PROTACs (Proteolysis Targeting Chimeras)
Potent and selective WDR5 PROTAC® Degrader
Chemical Name:
N-(4'-((5-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-5-oxopentyl)carbamoyl)-4-(4-methylpiperazin-1-yl)-[1,1'-biphenyl]-3-yl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide
Purity:
≥95%
Selective EP300 Degrader (PROTAC®)
Chemical Name:
(2S,4R)-1-((S)-2-(8-(2-(4-(6-((R)-2-(((S)-2-(4-Cyanophenyl)propyl)amino)-2-phenylacetamido)pyridin-3-yl)-1H-pyrazol-1-yl)acetamido)octanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide
Purity:
≥95%
Potent and selective ENL Degrader (PROTAC®)
Chemical Name:
5-[4-(Dimethylcarbamoyl)-3-hydroxyphenyl]-N-[(1R)-6-[[10-[[(2S)-1-[(2S,4R)-4-hydroxy-2-[[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]carbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]amino]-10-oxodecyl]carbamoyl]-2,3-dihydro-1H-inden-1-yl]-1,2-oxazole-3-carboxamide
Purity:
≥97%
Potent and selective LRRK2 Degrader (PROTAC®)
Chemical Name:
(2S,4R)-1-((R)-3-((((1r,4R)-4-((4-(4-((5-Chloro-4-(methyl-λ2-azaneyl)pyrimidin-2-yl)amino)-3-methoxybenzoyl)piperazin-1-yl)methyl)cyclohexyl)methyl)thio)-2-(1-fluorocyclopropane-1-carboxamido)-3-methylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity:
≥98%
