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PlGF-2 Products
Placenta growth factor (PlGF) is a dimeric growth factor in the PDGF/VEGF family. Alternative splicing generates at least three human PlGF isoforms PlGF-1, PlGF-2, and PlGF-3. PlGF-2 is the only isoform that contains a heparin binding region. It is expressed by villous trophoblasts, decidual cells, erythroblasts, keratinocytes, and some endothelial cells. PlGF competes with VEGF for binding and activating VEGF R1/Flt-1. This results in increased angiogenesis by making more VEGF available for activation of VEGF R2. PlGF-2 also exhibits heparin dependent binding of Neuropilins-1 and -2 which serve as VEGF co-receptors. It can inhibit nerve growth cone collapse and induce monocyte production of inflammatory cytokines including VEGF.
9 results for "PlGF-2" in Products
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PlGF-2 Products
Placenta growth factor (PlGF) is a dimeric growth factor in the PDGF/VEGF family. Alternative splicing generates at least three human PlGF isoforms PlGF-1, PlGF-2, and PlGF-3. PlGF-2 is the only isoform that contains a heparin binding region. It is expressed by villous trophoblasts, decidual cells, erythroblasts, keratinocytes, and some endothelial cells. PlGF competes with VEGF for binding and activating VEGF R1/Flt-1. This results in increased angiogenesis by making more VEGF available for activation of VEGF R2. PlGF-2 also exhibits heparin dependent binding of Neuropilins-1 and -2 which serve as VEGF co-receptors. It can inhibit nerve growth cone collapse and induce monocyte production of inflammatory cytokines including VEGF.
9 results for "PlGF-2" in Products
| Sensitivity : | 1.84 pg/mL |
| Assay Range : | 23.4 - 1,500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma) |
| Applications : | ELISA |
| Source : | Sf 21 (baculovirus) |
| Accession # : | Q544A5 |
| Applications : | Binding Activity |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #62526 |
| Applications : | Block/Neutralize, Western Blot |
| Assay Range : | 15.6 - 1,000 pg/mL |
| Applications : | ELISA |
| Source : | CHO |
| Accession # : | NP_002623 |
| Applications : | Bioactivity |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #62503 |
| Applications : | ELISA Capture |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #62526R |
| Applications : | Block/Neutralize |
