Skip to main content

120 results for "PDGF-D" in Products

PDGF-D Products

Platelet-derived growth factor-D (PDGF-D) is a cytokine that associates into disulfide-linked homodimers that bind to PDGF R beta and trigger signaling through PDGF R beta homodimers and PDGF R alpha/beta heterodimers. It is secreted as a latent homodimer which is activated by proteolysis to release a bioactive disulfide-linked dimer. PDGF-DD is widely expressed in embryonic and adult tissues. It functions as a growth factor for renal artery smooth muscle cells and lens epithelial cells, and as a macrophage chemoattractant. PDGF-DD is upregulated in and contributes to several disease states, including renal and hepatic fibrosis, mesangial proliferative glomerulopathy, pulmonary lymphoid infiltration, and many cancers.

 

Source: NS0
Accession #: Q925I7.1
Applications: BA
Recombinant Mouse PDGF-D Protein Bioactivity
Reactivity: Human, Mouse, Rat
Details: Mouse IgG1 Monoclonal Clone #OTI1C1
Applications: WB, Flow, CyTOF-ready
Western Blot: PDGF-D/SCDGFB Antibody (OTI1C1)Azide and BSA Free [NBP2-73305]
(2)
Reactivity: Human, Mouse, Rat
Details: Mouse IgG1 Monoclonal Clone #OTI1C1
Applications: WB, Flow
(2)
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: ICC/IF
Immunocytochemistry/ Immunofluorescence: PDGF-D/SCDGFB Antibody [NBP2-55053]
Results Per Page
5 10 25 50
/ 5