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PBR Products
The peripheral benzodiazepine receptor (PBR) is named for its affinity for benzodiazepines and its initial description in peripheral tissues. This is opposite to the central benzodiazepine receptors (CBRs) of the CNS that are primarily responsible for the relaxant, anticonvulsant, and anxiolytic effects of benzodiazepines. PBR is a transmembrane protein associated with the outer mitochondrial membrane. It has been implicated in several physiological functions, including steroidogenesis, mitochondrial respiratory control, and cell growth, survival, differentiation, and chemotaxis.
7 results for "PBR" in Products
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PBR Products
The peripheral benzodiazepine receptor (PBR) is named for its affinity for benzodiazepines and its initial description in peripheral tissues. This is opposite to the central benzodiazepine receptors (CBRs) of the CNS that are primarily responsible for the relaxant, anticonvulsant, and anxiolytic effects of benzodiazepines. PBR is a transmembrane protein associated with the outer mitochondrial membrane. It has been implicated in several physiological functions, including steroidogenesis, mitochondrial respiratory control, and cell growth, survival, differentiation, and chemotaxis.
7 results for "PBR" in Products
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2393B |
| Applications : | Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot |
Mitochondrial targeting AUTAC Degrader
| Chemical Name : | N-[(16R)-16-[[[2-Amino-9-[(4-fluorophenyl)methyl]-6,9-dihydro-6-oxo-1H-purin-8-yl]thio]methyl]-15,18-dioxo-4,7,10-trioxa-14,17-diazanonadec-1-yl]-α-oxo-2-phenyl-1H-indole-3-acetamide |
| Purity : | ≥98% (HPLC) |
Benzodiazepine antagonist
| Alternate Names : | Ro 15-1788 |
| Chemical Name : | 8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, ethyl ester |
| Purity : | ≥99% (HPLC) |
Potent, specific ligand for mitochondrial DBI receptor
| Chemical Name : | N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide |
| Purity : | ≥98% (HPLC) |
Positive allosteric modulator of benzodiazepine site
| Chemical Name : | 2-(4-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one-1,1-dioxide |
| Purity : | ≥99% (HPLC) |
Selective TSPO ligand
| Alternate Names : | XBD173 |
| Chemical Name : | N-Ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)-9H-purine-9-acetamide |
| Purity : | ≥98% (HPLC) |
Benzodiazepine inverse agonist
| Chemical Name : | N-Methyl-β-carboline-3-carboxamide |
| Purity : | ≥99% (HPLC) |
